Article
Targeted Disruption of the FGF2 Gene Does Not Prevent Choroidal Neovascularization in a Murine Model
1 Nov 1998
Abstract excerpt
Choroidal neovascularization (CNV) is the major cause of severe visual loss in patients with age-related macular degeneration. Laser treatment is helpful for a minority of patients with CNV, and development of new treatments is hampered by a poor understanding of the molecular signals involved. Several lines of evidence have suggested that basic fibroblast growth factor (FGF2) plays a role in stimulating CNV. In...
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