Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Macrophages Inhibit Neovascularization in a Murine Model of Age-Related Macular Degeneration

10 Aug 2006

Abstract excerpt

BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of blindness in people over 50 y of age in at least three continents. Choroidal neovascularization (CNV) is the process by which abnormal blood vessels develop underneath the retina. CNV develops in 10% of patients with AMD but accounts for up to 90% of the blindness from AMD. Although the precise etiology of CNV in AMD remains unknown, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ocular Diseases and Behçet’s Syndrome
Share to Retinal and Macular Surgery
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16903779
DOI: 10.1371/journal.pmed.0030310

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Macrophages Inhibit Neovascularization in a Murine Model of Age-Related Macular DegenerationPMID 16903779Read ↗

Different distributions of M1 and M2 macrophages in a mouse model of laser-induced choroidal neovascularizationSemantic proximity Read ↗

Age-Dependent Changes in FasL (CD95L) Modulate Macrophage Function in a Model of Age-Related Macular DegenerationSemantic proximity Read ↗

CD11c+ macrophages are proangiogenic and necessary for experimental choroidal neovascularizationSemantic proximity Read ↗

The critical role of ocular-infiltrating macrophages in the development of choroidal neovascularizationSemantic proximity Read ↗

VEGF-production by CCR2-dependent macrophages contributes to laser-induced choroidal neovascularization.Semantic proximity Read ↗

Senescence regulates macrophage activation and angiogenic fate at sites of tissue injury in miceSemantic proximity Read ↗

Role of macrophage in ocular neovascularizationSemantic proximity Read ↗

PGE2 promotes macrophage recruitment and neovascularization in murine wet-type AMD modelsSemantic proximity Read ↗

PlGF and VEGF-A/PlGF heterodimer are crucial for recruitment and activation of immune cells during choroid neovascularizationSemantic proximity Read ↗

Mechanism of Inflammation in Age-Related Macular DegenerationSemantic proximity Read ↗

MicroRNA-155 Inhibits Polarization of Macrophages to M2-Type and Suppresses Choroidal Neovascularization.Semantic proximity Read ↗

Proangiogenic characteristics of activated macrophages from patients with age-related macular degeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.