Back to search

Article

A Mouse Model for Laser-induced Choroidal Neovascularization

2015-12-27

Abstract excerpt

The mouse laser-induced choroidal neovascularization (CNV) model has been a crucial mainstay model for neovascular age-related macular degeneration (AMD) research. By administering targeted laser injury to the RPE and Bruch’s membrane, the procedure induces angiogenesis, modeling the hallmark pathology observed in neovascular AMD. First developed in non-human primates, the laser-induced CNV model has come to be im...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
26c0746d-9f99-5d39-918f-0e826e182af8
DOI
10.3791/53502-v
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A Mouse Model for Laser-induced Choroidal NeovascularizationDOI 10.3791/53502-v
A Mouse Model for Laser-induced Choroidal NeovascularizationSemantic proximity
Laser-induced choroidal neovascularization model to study age-related macular degeneration in miceSemantic proximity
Revisiting the mouse model of oxygen-induced retinopathySemantic proximity
Evaluation of sex differences in laser-induced choroidal neovascularization severity, phenotype and disease progressionSemantic proximity
REVIEW PAPER: Animals as Models of Age-Related Macular DegenerationSemantic proximity
Comparative Analysis of Molecular Landscape in Mouse Models and Patients Reveals Conserved Inflammation Pathways in Age-Related Macular DegenerationSemantic proximity
Mouse models of age-related macular degeneration.Semantic proximity
Studying Age‐Related Macular Degeneration Using Animal ModelsSemantic proximity
Molecular genetics of AMD and current animal models.Semantic proximity
Spontaneous CNV in a novel mutant mouse is associated with early VEGF-A-driven angiogenesis and late-stage focal edema, neural cell loss, and dysfunction.Semantic proximity
The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularizationSemantic proximity
Transgenic mouse models of corneal neovascularization: new perspectives for angiogenesis research.Semantic proximity
Select a neighboring publication to make it the new centre.