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Article

The anti-angiogenic role of discoidin domain receptor 2 (DDR2) in laser-induced choroidal neovascularization.

Journal of molecular medicine (Berlin, Germany) - 1 Feb 2015

Zhu Tong, Zhu Jie, Bu Xin, Zhao Hu, Zhang Shuya, Chang Yuan, Li Rong, Yao Libo, Wang Yusheng, Su Jin

Abstract excerpt

Choroidal neovascularization (CNV), an aberrant growth of blood vessels in the choroid layer of the eye, is a major cause of vision loss. In view of our recent finding that discoidin domain receptor 2 (DDR2), a collagen-binding receptor tyrosine kinase, is involved in control of vascular endothelial activity and tumor angiogenesis, the present study aims to investigate whether and how DDR2 affects the...

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Share to Adenoviridae
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neovascularization, Pathologic

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Source

Identifiers

PMID: 25355563
DOI: 10.1007/s00109-014-1213-7

Genes

DDR2
RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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