Article
Functional interactions of genes mediating convergent extension, knypek and trilobite, during the partitioning of the eye primordium in zebrafish.
Developmental biology - 15 Nov 1998
Marlow F, Zwartkruis F, Malicki J, Neuhauss S C, Abbas L, Weaver M, Driever W, Solnica-Krezel L
Abstract excerpt
Vertebrate eye development in the anterior region of the neural plate involves a series of inductive interactions dependent on the underlying prechordal plate and signals from the midline of the neural plate, including Hedgehog. The mechanisms controlling the spatiotemporal expression pattern of hedgehog genes are currently not understood. Cyclopia is observed in trilobite (tri) and knypek (kny) mutants with...
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