Article
Opposing interactions between homothorax and Lobe define the ventral eye margin of Drosophila eye.
Developmental biology - 15 Nov 2011
Singh Amit, Tare Meghana, Kango-Singh Madhuri, Son Won-Seok, Cho Kyung-Ok, Choi Kwang-Wook
Abstract excerpt
Patterning in multi-cellular organisms involves progressive restriction of cell fates by generation of boundaries to divide an organ primordium into smaller fields. We have employed the Drosophila eye model to understand the genetic circuitry responsible for defining the boundary between the eye and the head cuticle on the ventral margin. The default state of the early eye is ventral and depends on the function...
Topics
- Animals
- Animals, Genetically Modified
- Binding Sites
- Calcium-Binding Proteins
- Cell Nucleus
- Drosophila Proteins
- Drosophila melanogaster
- Eye
- Eye Proteins
- Female
- Homeodomain Proteins
