Article
No correlation of c-myc overexpression and p53 mutations in liposarcomas.
Virchows Archiv : an international journal of pathology - 1 Oct 1998
Schneider-Stock R, Walter H, Rys J, Radig K, Hoang-Vu C, Roessner A
Abstract excerpt
Although it is well known that oncogenesis is a multistep process involving the activation of normal cellular genes to become oncogenes and/or the inactivation of tumor suppressor genes, this process has seldom been investigated in soft tissue tumours. We screened a group of 36 liposarcomas for genetic abnormalities in the p53 tumour suppressor gene and c-myc oncogene. Altered c-myc gene expression was examined...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.