Article
Limited role of TP53 and TP53-related genes in myxoid liposarcoma.
Tumori - 1 Jan 2000
Pilotti S, Lavarino C, Mezzelani A, Della Torre C, Minoletti F, Sozzi G, Azzarelli A, Rilke F, Pierotti M A
Abstract excerpt
AIMS: Circumstantial evidence suggests that genetic changes may lead to tumor progression within the myxoid liposarcoma tumors (MLTs) carrying non-random chromosomal translocation t(12;16). METHODS: To address this subject an immunophenotypic analysis, applying antibodies against proteins encoded...
Topics
- DNA Mutational Analysis
- Genes, p53
- Humans
- Immunophenotyping
- In Situ Hybridization, Fluorescence
- Liposarcoma
- Liposarcoma, Myxoid
- Mutation
- Neoplasm Proteins
- Polymorphism, Single-Stranded Conformational
- Proto-Oncogene Proteins
- Reverse Transcriptase Polymerase Chain Reaction
- Tumor Cells, Cultured