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Article

Normal and functional TP53 in genetically stable myxoid/round cell liposarcoma.

PloS one - 1 Jan 2014

Ståhlberg Anders, Kåbjörn Gustafsson Christina, Engtröm Katarina, Thomsen Christer, Dolatabadi Soheila, Jonasson Emma, Li Chieh-Yuan, Ruff David, Chen Shiaw-Min, Åman Pierre

Abstract excerpt

Myxoid/round-cell liposarcoma (MLS/RCLS) is characterized by either the fusion gene FUS-DDIT3 or the less commonly occurring EWSR1-DDIT3 and most cases carry few or no additional cytogenetic changes. There are conflicting reports concerning the status and role of TP53 in MLS/RCLS. Here we analysed four MLS/RCLS derived cell lines for TP53 mutations, expression and function. Three SV40 transformed cell lines...

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Source

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Identifiers

PMID: 25393000
DOI: 10.1371/journal.pone.0113110
PMCID: PMC4231113

Genes

DDIT3
FUS
EWSR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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