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Article

p53 and brain tumors: from gene mutations to gene therapy.

Brain pathology (Zurich, Switzerland) - 1 Oct 1998

Fulci G, Ishii N, Van Meir E G

Abstract excerpt

The p53 tumor suppressor gene (TP53) is the most frequently altered gene in human cancer and is also found mutated in several types of brain tumors. Loss of p53 function plays a central role in the development of cancer. The characterization of the biochemical pathways by which p53 alteration tri...

Topics

Animals
Brain Neoplasms
Genes, p53
Genetic Therapy
Humans
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9804370
DOI: 10.1111/j.1750-3639.1998.tb00187.x
PMCID: PMC8098259

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9804370-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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