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Article

Fc receptor-mediated phagocytosis requires CDC42 and Rac1.

The EMBO journal - 2 Nov 1998

Massol P, Montcourrier P, Guillemot J C, Chavrier P

Abstract excerpt

At the surface of phagocytes, antibody-opsonized particles are recognized by surface receptors for the Fc portion of immunoglobulins (FcRs) that mediate their capture by an actin-driven process called phagocytosis which is poorly defined. We have analyzed the function of the Rho proteins Rac1 and CDC42 in the high affinity receptor for IgE (FcepsilonRI)-mediated phagocytosis using transfected rat basophil...

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Identifiers

PMID: 9799231
DOI: 10.1093/emboj/17.21.6219
PMCID: PMC1170948

Genes

CDC42

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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