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Article

Regulation of receptor-mediated endocytosis by Rho and Rac.

Nature - 11 Jul 1996

Lamaze C, Chuang T H, Terlecky L J, Bokoch G M, Schmid S L

Abstract excerpt

Pinocytosis and membrane ruffling are among the earliest and most dramatic cellular responses to stimulation by growth factors or other mitogens. The small Ras-related G proteins Rho and Rac have a regulatory role in membrane ruffling and activated Rho has been shown to stimulate pinocytosis when...

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Identifiers

PMID: 8700210
DOI: 10.1038/382177a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-8700210-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Membrane ruffling and macropinocytosis in A431 cells require cholesterol.Semantic proximity Read ↗

Integrin-mediated signals regulated by members of the rho family of GTPases.Semantic proximity Read ↗

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