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Article

Regulation of receptor-mediated endocytosis by Rho and Rac.

Nature - 11 Jul 1996

Lamaze C, Chuang T H, Terlecky L J, Bokoch G M, Schmid S L

Abstract excerpt

Pinocytosis and membrane ruffling are among the earliest and most dramatic cellular responses to stimulation by growth factors or other mitogens. The small Ras-related G proteins Rho and Rac have a regulatory role in membrane ruffling and activated Rho has been shown to stimulate pinocytosis when microinjected into Xenopus oocytes. In contrast to these well established effects of Rho and Rac on plasma membrane...

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Identifiers

PMID: 8700210
DOI: 10.1038/382177a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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