The Rac target NADPH oxidase p67phox interacts preferentially with Rac2 rather than Rac1.

doi:10.1074/jbc.271.1.83

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Article

The Rac target NADPH oxidase p67phox interacts preferentially with Rac2 rather than Rac1.

The Journal of biological chemistry - 5 Jan 1996

Dorseuil O, Reibel L, Bokoch G M, Camonis J, Gacon G

Abstract excerpt

NADPH oxidase is a plasma membrane enzyme of phagocytes generating superoxide anions which serve as bactericidal agents. Activation of this multimolecular enzyme minimally requires assembly at the membrane with flavocytochrome b558 of cytosolic components p47phox, p67phox, and Rac proteins. Rac1...

Topics

Amino Acid Sequence
Cloning, Molecular
Enzyme Activation
GTP-Binding Proteins
Humans
Molecular Sequence Data
Mutation
NADPH Dehydrogenase
NADPH Oxidases
Phosphoproteins
Substrate Specificity
rac GTP-Binding Proteins

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