Article
Integrin-mediated signals regulated by members of the rho family of GTPases.
The Journal of cell biology - 27 Jul 1998
Clark E A, King W G, Brugge J S, Symons M, Hynes R O
Abstract excerpt
The organization of the actin cytoskeleton can be regulated by soluble factors that trigger signal transduction events involving the Rho family of GTPases. Since adhesive interactions are also capable of organizing the actin-based cytoskeleton, we examined the role of Cdc42-, Rac-, and Rho-depend...
Topics
- Actins
- Animals
- Cell Adhesion
- Cell Cycle Proteins
- Cell Line
- Cytoskeleton
- Fibronectins
- GTP Phosphohydrolases
- GTP-Binding Proteins
- GTPase-Activating Proteins
- Integrins
- Mutation
- Rats
- Signal Transduction
- cdc42 GTP-Binding Protein
- rhoA GTP-Binding Protein