Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor Necrosis Factor Primes Hepatocytes for Dna Replication in the Rat

1 Nov 1998

Abstract excerpt

Signaling through tumor necrosis factor receptor type 1 (TNFR-1) using a pathway that involves nuclear factor kappaB (NF-kappaB), interleukin-6 (IL-6), and STAT3 is required for the initiation of liver regeneration. We have proposed that TNF primes hepatocytes to respond to the mitogenic effect of growth factors, but so far, there has been no experimental demonstration that TNF enhances growth factor responses of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver physiology and pathology
Share to Organ Transplantation Techniques and Outcomes
Share to Pediatric Hepatobiliary Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9794905
DOI: 10.1002/hep.510280509

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor Necrosis Factor Primes Hepatocytes for Dna Replication in the RatPMID 9794905Read ↗

Hepatocyte growth factor induces hepatocyte proliferation in vivo and allows for efficient retroviral-mediated gene transfer in miceSemantic proximity Read ↗

Transcriptional Regulatory Signals Define Cytokine-Dependent and -Independent Pathways in Liver RegenerationSemantic proximity Read ↗

Transcriptional control of liver regenerationSemantic proximity Read ↗

Pro-inflammatory Cytokines Tumor Necrosis Factor α and Interleukin-6 and Survival Factor Epidermal Growth Factor Positively Regulate the Murine GSTA4 Enzyme in HepatocytesSemantic proximity Read ↗

The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes.Semantic proximity Read ↗

Hepatocyte growth factor in transgenic mice: Effects on hepatocyte growth, liver regeneration and gene expressionSemantic proximity Read ↗

[Molecular biology of hepatocyte growth factor (HGF)].Semantic proximity Read ↗

Tumor Necrosis Factor Inhibits Spread of Hepatitis C Virus Among Liver Cells, Independent From Interferons.Semantic proximity Read ↗

Liver regeneration and hepatocarcinogenesis in transforming growth factor-α-targeted miceSemantic proximity Read ↗

Oxidative mitochondrial DNA damage and deletion in hepatocytes of rejecting liver allografts in rats: role of TNF-alpha.Semantic proximity Read ↗

Cytokine gene expression by Kupffer cells in experimental alcoholic liver diseaseSemantic proximity Read ↗

Transforming growth factor β modulates growth and differentiation of fetal hepatocytes in primary cultureSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.