Article
Hepatocyte growth factor in transgenic mice: Effects on hepatocyte growth, liver regeneration and gene expression
1 Apr 1994
Abstract excerpt
Attention has recently been focused on hepatocyte growth factor as a major candidate factor in liver regeneration because it is the most potent known mitogen for hepatocytes in vitro. However, hepatocyte growth factor also displays diverse activities in vitro as scatter factor, as an epithelial morphogen, as a pluripotent mitogen and as a growth inhibitor. Consequently, we developed transgenic mice that expressed...
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