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Article

Cytokine gene expression by Kupffer cells in experimental alcoholic liver disease

1 Oct 1995

Abstract excerpt

Kupffer cell-derived cytokines are believed to play pivotal paracrine roles in the pathogenesis of alcoholic liver disease (ALD). To evaluate this hypothesis, Kupffer cell gene expression of tumor necrosis factor-alpha (TNFα), interleukin (IL)-6, and transforming growth factor-beta 1 (TGFβ1) were directly examined in the rat model of ALD. Kupffer cells were isolated from the model after 10 and 17 weeks of...

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PMID: 7557885
DOI: 10.1002/hep.1840220441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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