Article
[Molecular biology of hepatocyte growth factor (HGF)].
Nihon rinsho. Japanese journal of clinical medicine - 1 Feb 1993
Matsuda Y, Nakamura T
Abstract excerpt
Hepatocyte growth factor (HGF) is the most potent mitogen of mature hepatocytes in primary culture, and is a molecule composed of 69 kD alpha-chain and 34 kD beta-chain. HGF predominantly acts on various epithelial cells as a mitogen, motogen and a morphogen. HGF mRNA and HGF protein increases rapidly in the liver and plasma of rats with liver injury such as hepatitis, ischemia, physical crush and partial...
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