Transforming growth factor β modulates growth and differentiation of fetal hepatocytes in primary culture

doi:10.1002/jcp.1041650221

Article

Transforming growth factor β modulates growth and differentiation of fetal hepatocytes in primary culture

1 Nov 1995

Abstract excerpt

Fetal hepatocytes in primary culture are cells capable to carry out both proliferation and differentiation processes simultaneously. Previous studies have shown that these cells respond to mitogens, such as hepatocyte growth factor (HGF) or epidermal growth factor (EGF), inducing the expression of early genes, such as fos and myc. The transforming growth factor-beta (TGF-beta) family is one of the most...

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