Article
DNA polymorphisms in the ACE gene, serum ACE activity and the risk of nephropathy in insulin-dependent diabetes mellitus.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Oct 1998
Freire M B, van Dijk D J, Erman A, Boner G, Warram J H, Krolewski A S
Abstract excerpt
BACKGROUND: To determine the relationship between DNA polymorphisms in the angiotensin I converting enzyme (ACE) gene, serum ACE activity and the risk of diabetic nephropathy. METHODS: A case-control study was carried out in a population of Jewish insulin-dependent diabetes mellitus (IDDM) patien...
Topics
- Alleles
- Case-Control Studies
- Child
- DNA
- DNA Probes
- DNA Transposable Elements
- Diabetes Mellitus, Type 1
- Diabetic Nephropathies
- Female
- Gene Deletion
- Genotype
- Humans
- Male
- Peptidyl-Dipeptidase A
- Polymerase Chain Reaction