Article
Genetic predisposition to diabetic nephropathy. Evidence for a role of the angiotensin I--converting enzyme gene.
Diabetes - 1 May 1994
Doria A, Warram J H, Krolewski A S
Abstract excerpt
In search of genetic determinants of susceptibility to diabetic nephropathy, we examined the association between DNA sequence differences at the locus of angiotensin I-converting enzyme (ACE) and renal complications in 151 insulin-dependent diabetes mellitus (IDDM) patients with a diabetes durati...
Topics
- Adult
- Age of Onset
- Albuminuria
- Blood Glucose
- DNA
- Deoxyribonucleases, Type II Site-Specific
- Diabetes Mellitus, Type 1
- Diabetic Nephropathies
- Exons
- Follow-Up Studies
- Genetic Carrier Screening
- Genetic Predisposition to Disease
- Genotype
- Haplotypes
- Humans
- Hyperglycemia
- Hypertension
- Kidney Function Tests