Article
Lack of association of angiotensin II type 1 receptor gene polymorphism with diabetic nephropathy in insulin-dependent diabetes mellitus.
Diabetic medicine : a journal of the British Diabetic Association - 1 Oct 1997
Chowdhury T A, Dyer P H, Kumar S, Gough S C, Gibson S P, Rowe B R, Smith P R, Dronsfield M J, Marshall S M, Mackin P, Dean J D, Morris P J, Davies S, Dunger D B, Boulton A J, Barnett A H, Bain S C
Abstract excerpt
Several observations suggest that inherited factors are influential in the development of nephropathy in patients with insulin-dependent diabetes mellitus (IDDM). Genetic components of the renin angiotensin system are possible candidate genes. The aim of this study was to determine the role of the hypertension associated angiotensin II type 1 receptor (AT1R) gene A1166C polymorphism in susceptibility to...
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