Article
Influence of genetic variability at the ACE locus in intron 16 on Diabetic Nephropathy in T1DM patients.
Indian journal of physiology and pharmacology - 1 Jan 2000
Parchwani Deepak N, Kesari M G, Patel Digisha D, Patel Darshan J
Abstract excerpt
BACKGROUND: Diallelic [insertion/deletion (L/D)] polymorphism in the angiotensin-converting enzyme (ACE) gene has been reported inconsistently as being associated with risk of diabetic nephropathy (DN). OBJECTIVE: To examine the three ACE poly-morphic variants in intron 16 for a possible role in modulating DN in T1DM patients from Kutch region, Gujarat. DESIGN AND SETTING: I/D polymorphism in intron 16 of the ACE...
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