Article
Angiotensin I-converting enzyme gene polymorphisms: relationship to nephropathy in patients with non-insulin dependent diabetes mellitus.
Journal of the American Society of Nephrology : JASN - 1 Sept 1998
Grzeszczak W, Zychma M J, Lacka B, Zukowska-Szczechowska E
Abstract excerpt
Nephropathy is a frequent complication of long-term diabetes. Strong evidence exists that genetic predisposition plays a major role in the development of diabetic nephropathy. The role of the angiotensin I-converting enzyme gene (ACE) in the susceptibility to nephropathy in diabetes, especially i...
Topics
- Aged
- Albuminuria
- Alleles
- Analysis of Variance
- Base Sequence
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Female
- Genetic Markers
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Peptidyl-Dipeptidase A
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Reference Values
- Sensitivity and Specificity