Article
Genetic polymorphisms of the renin-angiotensin system and the outcome of focal segmental glomerulosclerosis in children.
Kidney international - 1 Dec 1998
Frishberg Y, Becker-Cohen R, Halle D, Feigin E, Eisenstein B, Halevy R, Lotan D, Juabeh I, Ish-Shalom N, Magen D, Shvil Y, Sinai-Treiman L, Drukker A
Abstract excerpt
BACKGROUND: The clinical course of primary focal segmental glomerulosclerosis (FSGS) in children is variable, with some patients having a much more rapidly progressing course than others. The purpose of our study was to compare the frequency of three polymorphisms of the renin-angiotensin system (RAS) in children with FSGS with that in healthy controls of matching ethnic groups, and to determine whether the...
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