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Genetic polymorphisms of the renin–angiotensin system and complications of insulin‐dependent diabetes mellitus

1 Jul 2000

Abstract excerpt

OBJECTIVE: Patients with insulin-dependent diabetes mellitus (IDDM) have a high risk of developing diabetic nephropathy, retinopathy and cardiovascular diseases. The contribution of gene polymorphisms of the renin angiotensin system to these complications is controversial and may differ among populations. METHODS: In 257 Dutch IDDM patients (188 with urinary albumin excretion (UAE) <30 mg/24 h), logistic...

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PMID: 10862638
DOI: 10.1093/ndt/15.7.1000

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