Article
Angiotensin-Converting Enzyme Gene Polymorphism in Children with Idiopathic Nephrotic Syndrome, Effect on Biopsy Findings.
Fetal and pediatric pathology - 1 Aug 2017
Monajemzadeh Maryam, Hesami Mahshid, Shahsiah Reza, Vasei Mohammad, Hooshmand Safoora, Tanzifi Parin, Hajizadeh Niloofar, Ataei Neamatollah, Mehrkash Mehryar, Javadi Larijani Faezeh, Moghtaderi Mastaneh, Bazargani Behnaz, Khorvash Reza, Soleimanifar Narjes
Abstract excerpt
OBJECTIVE: Angiotensin converting enzyme (ACE) converts angiotensin I into angiotensin II. The ACE gene shows an I/D polymorphism, which correlates with ACE concentrations. The aim of this study is to evaluate the distribution of the ACE I/D genotype in children with idiopathic nephrotic syndrome (INS) and healthy controls and study the effect of this polymorphism on clinical and pathologic findings. METHODS: ACE...
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