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Article

Maximal transcriptional activation by the IHF protein of Escherichia coli depends on optimal DNA bending by the activator.

Molecular microbiology - 1 Oct 1998

Engelhorn M, Geiselmann J

Abstract excerpt

Transcriptional activation in prokaryotes can be mediated by at least two different mechanisms: direct contacts between the activator and RNA polymerase or modulation of the overall geometry of DNA. In the latter case, an activator protein that bends DNA favours contacts between the DNA upstream of the activator binding site and the back of RNA polymerase. The architectural protein integration host factor (IHF)...

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Identifiers

PMID: 9791186
DOI: 10.1046/j.1365-2958.1998.01078.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Maximal transcriptional activation by the IHF protein of Escherichia coli depends on optimal DNA bending by the activator.PMID 9791186Read ↗

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Genetic and biochemical analysis of the integration host factor of Escherichia coli.Semantic proximity Read ↗

Transcriptional activation by protein-induced DNA bending: evidence for a DNA structural transmission model.Semantic proximity Read ↗

The isolation and characterization of mutants of the integration host factor (IHF) of Escherichia coli with altered, expanded DNA-binding specificities.Semantic proximity Read ↗

Promoter protection by a transcription factor acting as a local topological homeostat.Semantic proximity Read ↗

Co-regulation by bent DNA. Functional substitutions of the integration host factor site at sigma 54-dependent promoter Pu of the upper-TOL operon by intrinsically curved sequences.Semantic proximity Read ↗

Participation of the flank regions of the integration host factor protein in the specificity and stability of DNA binding.Semantic proximity Read ↗

Genetic Approaches to Study the Interplay Between Transcription and Nucleoid-Associated Proteins in Escherichia coli.Semantic proximity Read ↗

A role for activator-mediated TFIIB recruitment in diverse aspects of transcriptional regulation.Semantic proximity Read ↗

Mutants of Escherichia coli integration host factor: DNA-binding and recombination properties.Semantic proximity Read ↗

IHF redistributes bound initiator protein, DnaA, on supercoiled oriC of Escherichia coli.Semantic proximity Read ↗

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