Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional activation by protein-induced DNA bending: evidence for a DNA structural transmission model.

Proceedings of the National Academy of Sciences of the United States of America - 6 Feb 1996

Parekh B S, Hatfield G W

Abstract excerpt

Integration host factor (IHF) is a DNA-bending protein that binds to an upstream activating sequence (UAS1) and, on a negatively supercoiled DNA template, activates transcription from the ilvPG promoter of the ilvG-MEDA operon of Escherichia coli. The transcriptional initiation site of the ilvGMEDA operon is located 92 bp downstream of UAS1. Activation is still observed when the orientation of the upstream IHF...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Binding Sites

Share to DNA-Binding Proteins

Share to Escherichia coli

Share to Genotype

Share to Kinetics

Share to Molecular Sequence Data

Source

Open in PubMed Open full text

Identifiers

PMID: 8577735
DOI: 10.1073/pnas.93.3.1173
PMCID: PMC40051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional activation by protein-induced DNA bending: evidence for a DNA structural transmission model.PMID 8577735Read ↗

Activation of transcription initiation from a stable RNA promoter by a Fis protein-mediated DNA structural transmission mechanism.Semantic proximity Read ↗

Maximal transcriptional activation by the IHF protein of Escherichia coli depends on optimal DNA bending by the activator.Semantic proximity Read ↗

Promoter protection by a transcription factor acting as a local topological homeostat.Semantic proximity Read ↗

Participation of the flank regions of the integration host factor protein in the specificity and stability of DNA binding.Semantic proximity Read ↗

Alterations in the p'R promoter of coliphage lambda modify both its activity and interaction with the integration host factor (IHF).Semantic proximity Read ↗

Participation of IHF and a distant UP element in the stimulation of the phage lambda PL promoter.Semantic proximity Read ↗

Thermoregulation of Shigella and Escherichia coli EIEC pathogenicity. A temperature‐dependent structural transition of DNA modulates accessibility of virF promoter to transcriptional repressor H‐NSSemantic proximity Read ↗

DNA binding and bending are necessary but not sufficient for Fis-dependent activation of rrnB P1.Semantic proximity Read ↗

xUBF contains a novel dimerization domain essential for RNA polymerase I transcription.Semantic proximity Read ↗

Eukaryotic HMGB proteins as replacements for HU in E. coli repression loop formation.Semantic proximity Read ↗

Influence of DNA geometry on transcriptional activation in Escherichia coli.Semantic proximity Read ↗

Role of upstream activation sequences and integration host factor in transcriptional activation by the constitutively active prokaryotic enhancer-binding protein PspF.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.