Article
Influence of DNA geometry on transcriptional activation in Escherichia coli.
The EMBO journal - 1 Oct 1996
Déthiollaz S, Eichenberger P, Geiselmann J
Abstract excerpt
Transcription from many Escherichia coli promoters can be activated by the cAMP-CRP complex bound at different locations upstream of the promoter. At some locations the mechanism of activation involves direct protein-protein contacts between CRP and the RNA polymerase. We positioned the CRP binding site at various distances from the transcription start site of the malT promoter and measured the in vivo activities...
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