Article
Impact of Helicobacter hepaticus infection in B6C3F1 mice from twelve National Toxicology Program two-year carcinogenesis studies.
Toxicologic pathology - 1 Jan 2000
Hailey J R, Haseman J K, Bucher J R, Radovsky A E, Malarkey D E, Miller R T, Nyska A, Maronpot R R
Abstract excerpt
Male and female B6C3F1 mice from 12 National Toxicology Program (NTP) 2-yr carcinogenesis studies were found to be infected with Helicobacter hepaticus. Many of the male mice from 9 of these studies had an associated hepatitis (affected studies). Helicobacter hepaticus has been reported to be ass...
Topics
- Animals
- Carcinogenicity Tests
- Cell Cycle
- Female
- Genes, ras
- Helicobacter
- Helicobacter Infections
- Hepatitis
- Liver Neoplasms, Experimental
- Male
- Mice
- Mice, Inbred Strains