Article
Impact of Helicobacter hepaticus infection in B6C3F1 mice from twelve National Toxicology Program two-year carcinogenesis studies.
Toxicologic pathology - 1 Jan 2000
Hailey J R, Haseman J K, Bucher J R, Radovsky A E, Malarkey D E, Miller R T, Nyska A, Maronpot R R
Abstract excerpt
Male and female B6C3F1 mice from 12 National Toxicology Program (NTP) 2-yr carcinogenesis studies were found to be infected with Helicobacter hepaticus. Many of the male mice from 9 of these studies had an associated hepatitis (affected studies). Helicobacter hepaticus has been reported to be associated with an increased incidence of hepatitis and hepatocellular neoplasms in the A/JCr male mouse. We attempted to...
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