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Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens

22 Oct 2009

Abstract excerpt

BACKGROUND AND AIMS: Hepatocellular carcinoma (HCC) frequently results from synergism between chemical and infectious liver carcinogens. Worldwide, the highest incidence of HCC is in regions endemic for the foodborne contaminant aflatoxin B1 (AFB1) and hepatitis B virus (HBV) infection. Recently, gut microbes have been implicated in multisystemic diseases including obesity and diabetes. Here, the hypothesis that...

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PMID: 19850960
DOI: 10.1136/gut.2009.183749

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