Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Review of studies concerning the tumorigenicity of 2-butoxyethanol in B6C3F1 mice and its relevance for human risk assessment.

Journal of toxicology and environmental health. Part B, Critical reviews - 1 Jan 2000

Boatman Rodney, Corley Richard, Green Trevor, Klaunig James, Udden Mark

Abstract excerpt

The U.S. National Toxicology Program (NTP) has completed 2-yr inhalation exposures in rats and mice with 2-butoxyethanol (BE). This review concerns the most significant findings from those studies and describes recent research into the mechanistic aspects of BE-mediated tumorigenesis in the mouse and the relevance of such effects to humans. Two tumor types were increased in B6C3F1 mice leading to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Administration, Oral
Share to Carcinogenicity Tests

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cocarcinogenesis

Share to Hemangiosarcoma

Share to Hemolysis

Share to Inhalation Exposure

Share to Kupffer Cells

Share to Neoplasms, Experimental

Source

Identifiers

PMID: 15371241
DOI: 10.1080/10937400490498084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Review of studies concerning the tumorigenicity of 2-butoxyethanol in B6C3F1 mice and its relevance for human risk assessment.PMID 15371241Read ↗

A Review of the Molecular Mechanisms of Chemically Induced Neoplasia in Rat and Mouse Models in National Toxicology Program Bioassays and Their Relevance to Human CancerSemantic proximity Read ↗

Differential genotoxic effects of subchronic exposure to ethyl tertiary butyl ether in the livers of Aldh2 knockout and wild-type mice.Semantic proximity Read ↗

1,3-Butadiene: Biomarkers and application to risk assessment.Semantic proximity Read ↗

Interactions between benzophenone-3 and dietary fat in mammary tumorigenesisSemantic proximity Read ↗

Mammalian models of chemically induced primary malignancies exploitable for imaging-based preclinical theragnostic research.Semantic proximity Read ↗

The Tg rasH2 Mouse in Cancer Hazard IdentificationSemantic proximity Read ↗

Evaluation of Possible Carcinogenic Risk to Humans Based on Liver Tumors in Rodent AssaysSemantic proximity Read ↗

CB6F1-rasH2 Mouse: Overview of Available DataSemantic proximity Read ↗

Spontaneous tumor incidence in rasH2 mice: review of internal data and published literature.Semantic proximity Read ↗

Nephrotoxicity and hepatotoxicity induced by inhaled bromodichloromethane in wild-type and p53-heterozygous mice.Semantic proximity Read ↗

Frequent p53 and H-ras mutations in benzene- and ethylene oxide-induced mammary gland carcinomas from B6C3F1 mice.Semantic proximity Read ↗

Impact of Helicobacter hepaticus infection in B6C3F1 mice from twelve National Toxicology Program two-year carcinogenesis studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.