Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interspecies comparison of liver carcinogenesis: implications for cancer risk assessment

1 Jan 1997

Abstract excerpt

The morphology of hepatocellular carcinoma is similar among mice, rats and humans, and the cellular pathogenesis shows features that are both similar and divergent among these species. However, major elements of etiology, molecular pathogenesis, and natural history differ between humans and rodents. As a reflection of these species-determined differences, rodents appear to be neither highly sensitive nor highly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Carcinogens and Genotoxicity Assessment
Share to Liver Disease Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9054591
DOI: 10.1093/carcin/18.1.59

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interspecies comparison of liver carcinogenesis: implications for cancer risk assessmentPMID 9054591Read ↗

Progress of non-human primate animal models of cancers.Semantic proximity Read ↗

Evaluation of Possible Carcinogenic Risk to Humans Based on Liver Tumors in Rodent AssaysSemantic proximity Read ↗

Past, present, and future of chemically induced hepatocarcinogenesis rodent models: Perspectives concerning classic and new cancer hallmarksSemantic proximity Read ↗

A Review of the Molecular Mechanisms of Chemically Induced Neoplasia in Rat and Mouse Models in National Toxicology Program Bioassays and Their Relevance to Human CancerSemantic proximity Read ↗

Relevance of Carcinogen-Induced Preclinical Cancer ModelsSemantic proximity Read ↗

Integrative genomic analysis of mouse and human hepatocellular carcinomaSemantic proximity Read ↗

Cancer in rodents: does it tell us about cancer in humans?Semantic proximity Read ↗

Use of early phenotypic in vivo markers to assess human relevance of an unusual rodent non-genotoxic carcinogen in vitro.Semantic proximity Read ↗

Modernizing Human Cancer Risk Assessment of Therapeutics.Semantic proximity Read ↗

Experimental mouse models for hepatocellular carcinoma researchSemantic proximity Read ↗

Hepatocellular Carcinomas in B6C3F1 Mice Treated with Ginkgo biloba Extract for Two Years Differ from Spontaneous Liver Tumors in Cancer Gene Mutations and Genomic PathwaysSemantic proximity Read ↗

Mutations in the ras proto-oncogene: clues to etiology and molecular pathogenesis of mouse liver tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.