Article
Diversity of Ig light chain variable region gene expression in fetal lambs.
International immunology - 1 Sept 1998
Hein W R, Dudler L
Abstract excerpt
The usage of lambda and kappa light chain variable region genes in peripheral fetal lamb B cells was assessed at intervals from 61 to 146 days of gestation (term = 150 days). Transcripts of 12 distinct Vlambda genes were identified, eight of which belonged to the previously described families I or II, while four segments defined a new Vlambda family, provisionally called family VI. A total of six different Vkappa...
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