Article
Diversity of Ig light chain variable region gene expression in fetal lambs.
International immunology - 1 Sept 1998
Hein W R, Dudler L
Abstract excerpt
The usage of lambda and kappa light chain variable region genes in peripheral fetal lamb B cells was assessed at intervals from 61 to 146 days of gestation (term = 150 days). Transcripts of 12 distinct Vlambda genes were identified, eight of which belonged to the previously described families I o...
Topics
- Animals
- B-Lymphocytes
- Base Sequence
- DNA, Complementary
- Embryo, Mammalian
- Female
- Gene Expression
- Gene Rearrangement, B-Lymphocyte, Light Chain
- Genes, Immunoglobulin
- Genetic Variation
- Humans
- Immunoglobulin Light Chains