Article
Developmental progression of equine immunoglobulin heavy chain variable region diversity.
Developmental and comparative immunology - 1 Sept 2013
Tallmadge Rebecca L, Tseng Chia T, King Rebecca A, Felippe M Julia B
Abstract excerpt
Humoral immunity is a critical component of the immune system that is established during fetal life and expands upon exposure to pathogens. The extensive humoral immune response repertoire is generated in large part via immunoglobulin (Ig) heavy chain variable region diversity. The horse is a useful model to study the development of humoral diversity because the placenta does not transfer maternal antibodies;...
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