Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human cord blood antibody repertoire. Mixed population of VH gene segments and CDR3 distribution in the expressed C alpha and C gamma repertoires.

Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 1993

Mortari F, Wang J Y, Schroeder H W

Abstract excerpt

Developmental regulation of the diversity of the antibody repertoire is associated with the controlled stepwise acquisition of Ag responsiveness during ontogeny. The development of IgG and IgA serum levels in humans lags far behind the maturation of the rest of the immune response. We cloned cord blood mononuclear cell C gamma and C alpha transcripts and compared them with a large database of > 250 published and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Oligodeoxyribonucleotides

Share to RNA, Messenger

Share to Sequence Alignment

Source

Identifiers

PMID: 8381834

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human cord blood antibody repertoire. Mixed population of VH gene segments and CDR3 distribution in the expressed C alpha and C gamma repertoires.PMID 8381834Read ↗

In-Depth Analysis of Human Neonatal and Adult IgM Antibody RepertoiresSemantic proximity Read ↗

Expressed antibody repertoires in human cord blood cells: 454 sequencing and IMGT/HighV-QUEST analysis of germline gene usage, junctional diversity, and somatic mutationsSemantic proximity Read ↗

High-throughput TCRB enrichment sequencing of human cord blood exhibited a distinct fetal T cell repertoire in the third trimester of pregnancySemantic proximity Read ↗

IgM Heavy Chain Complementarity-Determining Region 3 Diversity Is Constrained by Genetic and Somatic Mechanisms Until Two Months After BirthSemantic proximity Read ↗

Human Ig heavy chain CDR3 regions in adult bone marrow pre-B cells display an adult phenotype of diversity: evidence for structural selection of DH amino acid sequences.Semantic proximity Read ↗

The postnatal maturation of the immunoglobulin heavy chain IgG repertoire in human preterm neonates is slower than in term neonates.Semantic proximity Read ↗

Molecular analysis of VH regions expressed in the adult B-cell repertoire.Semantic proximity Read ↗

Dynamics of Individual T Cell Repertoires: From Cord Blood to CentenariansSemantic proximity Read ↗

Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell development.Semantic proximity Read ↗

T cell receptor repertoire diversity and clonal expansion in human neonates.Semantic proximity Read ↗

B cell development and proliferation of mature B cells in human fetal intestine.Semantic proximity Read ↗

The diversity of rearranged immunoglobulin heavy chain variable region genes in peripheral blood B cells of preterm infants is restricted by short third complementarity-determining regions but not by limited gene segment usage.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.