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Article

Diversity of immunoglobulin lambda light chain gene usage over developmental stages in the horse.

Developmental and comparative immunology - 1 Oct 2014

Tallmadge Rebecca L, Tseng Chia T, Felippe M Julia B

Abstract excerpt

To further studies of neonatal immune responses to pathogens and vaccination, we investigated the dynamics of B lymphocyte development and immunoglobulin (Ig) gene diversity. Previously we demonstrated that equine fetal Ig VDJ sequences exhibit combinatorial and junctional diversity levels comparable to those of adult Ig VDJ sequences. Herein, RACE clones from fetal, neonatal, foal, and adult lymphoid tissue were...

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Share to B-Lymphocytes
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Horses

Share to Immunoglobulin lambda-Chains

Share to Molecular Sequence Annotation

Share to Sequence Homology, Amino Acid

Share to V(D)J Recombination

Source

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Identifiers

PMID: 24726757
DOI: 10.1016/j.dci.2014.04.001
PMCID: PMC4107094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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