Article
[FK506 for the prophylaxis of graft-versus-host-disease after bone marrow transplantation from HLA-genotypically mismatched unrelated donor].
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Aug 1998
Nishida T, Haneda M, Kanie T, Murata M, Hamaguchi M, Minami S, Kodera Y
Abstract excerpt
Eleven leukemia patients who had undergone bone marrow transplants from HLA-A, B, DR genotypically mismatched unrelated donors received FK506 and short-term methotrexate as prophylaxis for graft-versus-host disease (GVHD). Grade III-IV acute GVHD developed in 2 of the patients, and chronic GVHD developed in 4 of the other patients. Adverse drug reaction included reversible nephrotoxicity, hyperglycemia (all...
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