Article
SNPs affecting the clinical outcomes of regularly used immunosuppressants.
Pharmacogenomics - 1 Apr 2018
Meng Huan-Yu, Luo Zhao-Hui, Hu Bo, Jin Wan-Lin, Yan Cheng-Kai, Li Zhi-Bin, Xue Yuan-Yuan, Liu Yu, Luo Yi-En, Xu Li-Qun, Yang Huan
Abstract excerpt
Recent studies have suggested that genomic diversity may play a key role in different clinical outcomes, and the importance of SNPs is becoming increasingly clear. In this article, we summarize the bioactivity of SNPs that may affect the sensitivity to or possibility of drug reactions that occur among the signaling pathways of regularly used immunosuppressants, such as glucocorticoids, azathioprine, tacrolimus,...
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