Article
[Predictive genomic markers for severe adverse drug reactions].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan - 1 Jan 2015
Saito Yoshiro, Kodama Susumu, Sugiyama Emiko, Nakamura Ryosuke
Abstract excerpt
Severe adverse drug reactions are an important issue to be considered during proper drug usage in postmarketing period. Most severe adverse reactions are idiosyncratic and unrelated to their pharmacological actions via primary targets. Although these reactions were not predictable, recent developments in the field of genomics have revealed closely associated markers responsible for some severe adverse reactions,...
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