Article
Function of zebrafish beta-catenin and TCF-3 in dorsoventral patterning.
Mechanisms of development - 1 Sept 1998
Pelegri F, Maischein H M
Abstract excerpt
We report the molecular cloning and expression of the zebrafish tcf-3 homologue and study its function and that of zebrafish betacat in dorsoventral patterning. Overexpression of mutant zTcf-3 products and Cadherin leads to a reduction in the expression of the dorsal-specific genes goosecoid and chording at the blastula stages, indicating a conserved role for betacat and tcf-3 in zebrafish dorsal axis induction....
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