Article
Induction of a secondary embryonic axis in zebrafish occurs following the overexpression of beta-catenin.
Mechanisms of development - 1 Oct 1995
Kelly G M, Erezyilmaz D F, Moon R T
Abstract excerpt
Formation of the vertebrate axis may involve a Wnt signaling cascade similar to the Drosophila wingless pathway. Zebrafish wnt8 is a candidate for involvement in axis specification insofar as it is expressed maternally and when overexpressed it can induce goosecoid, a transcription factor normally expressed in the embryonic shield. In this study we demonstrate that beta-catenin, a cadherin associated protein in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
