Rapid genotyping of hepatitis C virus by direct cycle sequencing of PCR-amplified cDNAs and capillary electrophoresis analysis.

doi:10.1016/s0923-2516(98)80003-4

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Article

Rapid genotyping of hepatitis C virus by direct cycle sequencing of PCR-amplified cDNAs and capillary electrophoresis analysis.

Research in virology - 1 Jan 2000

Doglio A, Laffont C, Thyss S, Lefebvre J C

Abstract excerpt

There is an increasing demand for the genotyping of hepatitis C virus (HCV), since it has been shown that different HCV genotypes are associated with distinct profiles of pathogenicity and responses to antiviral treatment. Hence, there is a need for a simple and precise genotyping assay for routi...

Topics

Automation
DNA, Complementary
Electrophoresis, Capillary
Female
Genotype
Hepacivirus
Hepatitis C
Humans
Male
RNA, Viral
Reagent Kits, Diagnostic
Reverse Transcriptase Polymerase Chain Reaction
Sequence Analysis, DNA

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