Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

cDNA sequencing of the 5' noncoding region (5' NCR) to determine hepatitis C genotypes in patients with chronic hepatitis C.

Digestive diseases and sciences - 1 May 1997

O'Brien C B, Henzel B S, Wolfe L, Gutekunst K, Moonka D

Abstract excerpt

Reports suggest that response to interferon-alpha therapy is influenced by both hepatitis C viral genotype and titer. Our aim was to determine if direct, automated, cycle sequencing of the PCR product from an HCV RNA detection assay could be used to reliably determine HCV genotype. In addition, the approach was used to determine the HCV genotype distribution in our patient population and to learn if there was a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Hepacivirus

Share to Hepatitis C

Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Share to RNA, Viral

Source

Identifiers

PMID: 9149068
DOI: 10.1023/a:1018813825486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

cDNA sequencing of the 5' noncoding region (5' NCR) to determine hepatitis C genotypes in patients with chronic hepatitis C.PMID 9149068Read ↗

Rapid genotyping of hepatitis C virus by direct cycle sequencing of PCR-amplified cDNAs and capillary electrophoresis analysis.Semantic proximity Read ↗

Hepatitis C virus gene sequencing as a tool for precise genotyping in the era of new direct antiviral agentsSemantic proximity Read ↗

Characterization of the genomic sequence of type V (or 3a) hepatitis C virus isolates and PCR primers for specific detectionSemantic proximity Read ↗

Important factors in reliable determination of hepatitis C virus genotype by use of the 5' untranslated region.Semantic proximity Read ↗

Use of sequence analysis of the NS5B region for routine genotyping of hepatitis C virus with reference to C/E1 and 5' untranslated region sequences.Semantic proximity Read ↗

Determination of hepatitis C virus genotype by direct sequence analysis of products generated with the Amplicor HCV test.Semantic proximity Read ↗

Determining hepatitis C genotype by analyzing the sequence of the NS5b region.Semantic proximity Read ↗

Sequence analysis of the 5' noncoding region of hepatitis C virus.Semantic proximity Read ↗

Genotyping of hepatitis C virus by melting curve analysis with SYBR Green I.Semantic proximity Read ↗

Development and evaluation of an automated hepatitis C virus NS5B sequence-based subtyping assay.Semantic proximity Read ↗

Hepatitis C virus genotyping based on 5' noncoding sequence analysis (Trugene).Semantic proximity Read ↗

Hepatitis C virus genotyping: interrogation of the 5' untranslated region cannot accurately distinguish genotypes 1a and 1b.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.