Coronavirus infection and demyelination. Sequence conservation of the S-gene during persistent infection of Lewis-rats.

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Article

Coronavirus infection and demyelination. Sequence conservation of the S-gene during persistent infection of Lewis-rats.

Advances in experimental medicine and biology - 1 Jan 1998

Wege H, Stühler A, Lassmann H, Wege H

Abstract excerpt

Coronaviruses display a large phenotypic variability, which may be an important factor for diversification and selection. Previous studies have demonstrated that the S-protein is an essential determinant of virulence and pathogenicity. Therefore we studied the S-gene as an indicator molecule for...

Topics

Animals
Cell Line
Coronavirus Infections
Demyelinating Diseases
Genetic Variation
Membrane Glycoproteins
Mice
Murine hepatitis virus
Rats
Rats, Inbred Lew
Spike Glycoprotein, Coronavirus
Viral Envelope Proteins
Virulence
Virus Latency

Source

Open in PubMed

Identifiers

PMID: 9782356

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9782356-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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