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Coronavirus infection and demyelination. Sequence conservation of the S-gene during persistent infection of Lewis-rats.

Advances in experimental medicine and biology - 1 Jan 1998

Wege H, Stühler A, Lassmann H, Wege H

Abstract excerpt

Coronaviruses display a large phenotypic variability, which may be an important factor for diversification and selection. Previous studies have demonstrated that the S-protein is an essential determinant of virulence and pathogenicity. Therefore we studied the S-gene as an indicator molecule for selection processes employing two different MHV-JHM variants. First, Lewis-rats were infected with MHV-JHM-Pi, a...

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PMID: 9782356

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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