Article
Phenotypic and functional characterization of CD8+ T lymphocytes from the central nervous system of rats with coronavirus JHM induced demyelinating encephalomyelitis.
Journal of neurovirology - 1 Dec 1995
Hein A, Schwender S, Imrich H, Sopper S, Czub M, Dörries R
Abstract excerpt
Intracerebral infection of Lewis (LEW) inbred rats with the neurotropic strain of the murine coronavirus JHM (JHMV) frequently results in a monophasic paralytic disease. In contrast, infection of Brown Norway (BN) inbred rats does not lead to clinical disease. Previous findings indicated that in...
Topics
- Animals
- Antibodies, Monoclonal
- Antibodies, Viral
- Brain
- CD8-Positive T-Lymphocytes
- Coronavirus Infections
- Demyelinating Diseases
- Encephalitis, Viral
- Flow Cytometry
- Histocompatibility Antigens Class I
- Histocompatibility Antigens Class II
- Multiple Myeloma
- Murine hepatitis virus
- Phenotype