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Article

Neurovirulence of six different murine coronavirus JHMV variants for rats.

Virus research - 1 Jun 1991

Matsubara Y, Watanabe R, Taguchi F

Abstract excerpt

Six variant viruses of the JHMV strain of murine coronavirus with large (cl-2, CNSV, DL and DS) or small (sp-4 and JHM-X) S proteins were compared in terms of their relative neurovirulence in weanling Lewis rats. Inoculation of various doses of the variants revealed that the cl-2 and CNSV were highly virulent and DL and DS were low-virulent, while sp-4 and JHM-X were avirulent. Pathological examination of rats...

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Identifiers

PMID: 1656623
DOI: 10.1016/0168-1702(91)90060-9
PMCID: PMC7133860

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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