Neurovirulence of six different murine coronavirus JHMV variants for rats.

doi:10.1016/0168-1702(91)90060-9

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Article

Neurovirulence of six different murine coronavirus JHMV variants for rats.

Virus research - 1 Jun 1991

Matsubara Y, Watanabe R, Taguchi F

Abstract excerpt

Six variant viruses of the JHMV strain of murine coronavirus with large (cl-2, CNSV, DL and DS) or small (sp-4 and JHM-X) S proteins were compared in terms of their relative neurovirulence in weanling Lewis rats. Inoculation of various doses of the variants revealed that the cl-2 and CNSV were hi...

Topics

Animals
Antigens, Viral
Coronaviridae
Coronaviridae Infections
Encephalomyelitis
Genetic Variation
Rats
Rats, Inbred Lew
Viral Proteins
Virulence

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