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Article

Assembly of productive T cell receptor delta variable region genes exhibits allelic inclusion.

The Journal of experimental medicine - 19 Oct 1998

Sleckman B P, Khor B, Monroe R, Alt F W

Abstract excerpt

The generation of a productive "in-frame" T cell receptor beta (TCR beta), immunoglobulin (Ig) heavy (H) or Ig light (L) chain variable region gene can result in the cessation of rearrangement of the alternate allele, a process referred to as allelic exclusion. This process ensures that most alphabeta T cells express a single TCR beta chain and most B cells express single IgH and IgL chains. Assembly of TCR alpha...

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Identifiers

PMID: 9782123
DOI: 10.1084/jem.188.8.1465
PMCID: PMC2213415

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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