First-stage autosomal genome screen in extended pedigrees suggests genes predisposing to low bone mineral density on chromosomes 1p, 2p and 4q.

doi:10.1038/sj.ejhg.5200169

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

First-stage autosomal genome screen in extended pedigrees suggests genes predisposing to low bone mineral density on chromosomes 1p, 2p and 4q.

European journal of human genetics : EJHG - 1 Jan 2000

Devoto M, Shimoya K, Caminis J, Ott J, Tenenhouse A, Whyte M P, Sereda L, Hall S, Considine E, Williams C J, Tromp G, Kuivaniemi H, Ala-Kokko L, Prockop D J, Spotila L D

Abstract excerpt

Osteoporosis is characterized by low bone density, and osteopenia is responsible for 1.5 million fractures in the United States annually. In order to identify regions of the genome which are likely to contain genes predisposing to osteopenia, we genotyped 149 members of seven large pedigrees havi...

Topics

Bone Density
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 2
Chromosomes, Human, Pair 4
Genetic Linkage
Genetic Predisposition to Disease
Genetic Testing
Humans
Microsatellite Repeats
Pedigree
Polymorphism, Genetic
Quantitative Trait, Heritable

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed

Identifiers

PMID: 9781060
DOI: 10.1038/sj.ejhg.5200169

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9781060-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.